Rocco Antonio Montone, MD, PhD; Riccardo Rinaldi, MD; Marco Giuseppe Del Buono, MD; Filippo Gurgoglione, MD; Giulia La Vecchia, MD; Michele Russo, MD, PhD; Andrea Caffè, MD; Francesco Burzotta, MD, PhD; Antonio Maria Leone, MD; Enrico Romagnoli, MD; Tommaso Sanna, MD; Gemma Pelargonio, MD; Carlo Trani, MD; Gaetano Antonio Lanza, MD; Giampaolo Niccoli, MD, PhD; Filippo Crea, MD, PhD
Lay Summary – Discussing the safety of Acetylcholine testing in pateints with INOCA
The subendocardial layers of the left ventricular wall are more sensitive to ischemia. Infarcts start in the subendocardium and progressively extend to the mid and subepicardial layers if ischemia is severe and prolonged enough. It is not exclusive of microvascular dysfunction, but of any mechanism that may precipitate myocardial infarction .
Ischemia is a condition of the cardiac muscle precipitated by local mechanisms. It is not directly related to hypoxia in the systemic circulation, with the possible exception of rare and dramatic conditions of systemic severe hypoxia.
Thomas F Lüscher
Lay Summary – Discusses gender bias in Cardiac research, testing and management
https://academic.oup.com/eurheartj/article/40/47/3807/5675348
Thomas J Ford, Paul Rocchicciolo, Richard Good, Margaret Entegart, Hany Eteiba, Stuart Watkins, Aadil Shaukat, Mitchell Lindsay, Keith Robertson, Stuart Hood, Eric Yii, Novalia Sidik, Adam Harvey, Augusto C Montezano, Elisabeth Beattie, Laura Haddow, Keith G Oldroyd, Rhian M Touyz, Colin Berry.
Lay Summary – Do INOCA conditions affect other areas of the body as well as the heart
http://academic.oup.com/eurheartj/article/39/46/4086/5079248
Thomas J Ford, Colin Berry.
Lay Summary – What was learned about INOCA conditions from the CorMicA Study
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545998/
Haseeb Rahman, David Corcoran, Muhammad Aetesam-ur-Rahman, Stephen P Hoole, Colin Berry, Divaka Perera.
Lay Summary – Defining the specific type of CMVD in patients can improve management
https://heart.bmj.com/content/105/20/1536
C. Noel Bairey Merz, Carl J Pepine, Mary Norine Walsh, Jerome L Fleg
Lay Summary – Discusses the current understanding of INOCA (2017) and the need for future trials and effective therapies
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385930
Peter Ong, Paolo G. Camici, John F Beltrame, Filippo Crea, Hiroaki Shimokawa, Udo Sechtem, Juan-Carlos Kaski, C. Noel Bairey Merz
Lay Summary – Defines standard criteria to investigate & diagnose microvascular angina
https://www.researchgate.net/publication/319612722_International_standardization_of_diagnostic_criteria_for_microvascular_angina
Professor Thomas F Lüscher
Lay Summary – What the term Acute Coronary Syndrome should now include.
https://academic.oup.com/eurheartj/article/40/15/1169/5450090
English 
Spanish