Myocardial ischaemia has been traditionally perceived as the consequence of atherosclerotic obstructions of the coronary vessels. More recently an overwhelming body of evidence has proven that atherosclerotic obstructions are just one of several mechanisms that can precipitate myocardial ischaemia. CAS, CMVD and Endothelial Dysfunction are included among the mechanisms that, in isolated fashion or in combination, may cause myocardial ischaemia
Coronary Artery Spasm — Clinical features, pathogenesis and treatment
Hirofumi Yasue, Yuji Mizuno, Eisaku Harada
Lay Summary – What it is, how it develops and what the treatments are (2019)
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403432
Prevalence and correlates of coronary microvascular dysfunction in heart failure with preserved ejection fraction: PROMIS-HFpEF
Sanjiv J Shah, Carolyn S P Lam, Sara Svedlund, Antti Saraste, Camilla Hage, Ru-San Tan, Lauren Beussink-Nelson, Ulrika Ljung Faxen, Maria Lagerstrom Fermer, Malin A Broberg, Li-Ming Gan, Lars H
Lay Summary – How common is Coronary Microvascular Dysfunction and is it associated with a particular type of heart failure.
https://academic.oup.com/eurheartj/article/39/37/3439/5077831
Systemic Microvascular Dysfunction in Microvascular and Vasospastic Angina
Thomas J Ford, Paul Rocchicciolo, Richard Good, Margaret Entegart, Hany Eteiba, Stuart Watkins, Aadil Shaukat, Mitchell Lindsay, Keith Robertson, Stuart Hood, Eric Yii, Novalia Sidik, Adam Harvey, Augusto C Montezano, Elisabeth Beattie, Laura Haddow, Keith G Oldroyd, Rhian M Touyz, Colin Berry.
Lay Summary – Do INOCA conditions affect other areas of the body as well as the heart
http://academic.oup.com/eurheartj/article/39/46/4086/5079248
Physiological Stratification of Patients With Angina Due to Coronary Microvascular Dysfunction
Haseeb Rahman, Ozan M. Demir, Faisal Khan, Matthew Ryan, Howard Ellis, Mark T. Mills, Amedeo Chiribiri, Andrew Webb and Divaka Perera
Lay Summary – 2020 research outlining two different types of Coronary Microvascular Dysfunction and the possible benefits of tailored treatments.
http://www.onlinejacc.org/content/75/20/2538
Testing for Coronary Microvascular Dysfunction
C Noel Bairey Merz
Lay Summary – Discusses the various testing available for CMD
https://jamanetwork.com/journals/jama/fullarticle/2755842