Haseeb Rahman, PhD, Ozan M. Demir, MBBS, Matthew Ryan, MBChB, Hannah McConkey, MBBS, Cian Scannell, MRes, Howard Ellis, BSc, Andrew Webb, PhD, Amedeo Chiribiri, PhD, and Divaka Perera, MD
Lay Summary – Investigating how the use of certain drugs in testing, can help accurate diagnosis and inform treatment.
https://www.ahajournals.org/doi/epub/10.1161/CIRCINTERVENTIONS.120.009019
Diagnosis of patients with angina and non-obstructive coronary disease in the catheter laboratory
Haseeb Rahman, David Corcoran, Muhammad Aetesam-ur-Rahman, Stephen P Hoole, Colin Berry, Divaka Perera.
Lay Summary – Defining the specific type of CMVD in patients can improve management
https://heart.bmj.com/content/105/20/1536
Ischemia and No Obstructive Coronary Artery Disease (INOCA): Developing Evidence-based Therapies and Research Agenda for the Next Decade
C. Noel Bairey Merz, Carl J Pepine, Mary Norine Walsh, Jerome L Fleg
Lay Summary – Discusses the current understanding of INOCA (2017) and the need for future trials and effective therapies
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385930
The Parallel Tales of Microvascular Angina and Heart Failure With Preserved Ejection Fraction: A Paradigm Shift
Filippo Crea, C Noel Bairey Merz, John F Beltrame, Juan-Carlos Kaski, Hisao Ogawa, Peter Ong, Udo Sechtem, Hiroaki Shimokawa, Paolo G Camici, Coronary Vasomotion Disorders International Study Group (COVADIS)
Lay Summary – Shows similarities in the lack of understanding in these two conditions
https://academic.oup.com/eurheartj/article/38/7/473/2422085
Small‐Vessel Disease in the Heart and Brain: Current Knowledge, Unmet Therapeutic Need, and Future Directions
Colin Berry, Novalia Sidik, Anthony Pereira, Thomas J Ford, Rhian M Touyz, Juan-Carlos Kaski and Atticus H Hainsworth
Lay Summary – Can CAS and CMVD affect other organs, in particular the brain.
https://www.ahajournals.org/doi/10.1161/JAHA.118.011104
Physiological Stratification of Patients With Angina Due to Coronary Microvascular Dysfunction
Haseeb Rahman, Ozan M. Demir, Faisal Khan, Matthew Ryan, Howard Ellis, Mark T. Mills, Amedeo Chiribiri, Andrew Webb and Divaka Perera
Lay Summary – 2020 research outlining two different types of Coronary Microvascular Dysfunction and the possible benefits of tailored treatments.
http://www.onlinejacc.org/content/75/20/2538
Testing for Coronary Microvascular Dysfunction
C Noel Bairey Merz
Lay Summary – Discusses the various testing available for CMD
https://jamanetwork.com/journals/jama/fullarticle/2755842
International standardization of diagnostic criteria for microvascular angina
Peter Ong, Paolo G. Camici, John F Beltrame, Filippo Crea, Hiroaki Shimokawa, Udo Sechtem, Juan-Carlos Kaski, C. Noel Bairey Merz
Lay Summary – Defines standard criteria to investigate & diagnose microvascular angina
https://www.researchgate.net/publication/319612722_International_standardization_of_diagnostic_criteria_for_microvascular_angina
Reappraisal of Ischaemic Heart Disease
Juan-Carlos Kaski, Filippo Crea, Bernard J Gersh and Paolo G Camici
Lay Summary – Updates the definition, symptoms, diagnosis & therapies available for Microvascular Angina (2018)
https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.118.031373
Ischaemia without obstructive coronary artery disease: the pathophysiology of microvascular dysfunction
Aish Sinha, Haseeb Rahman, Divaka Perera
Lay Summary – Discusses the causes and processes of Microvascular Dysfunction.
https://pubmed.ncbi.nlm.nih.gov/32852345/